AdventuresInLivingTerminallyOptimistic

What a long strange trip the past month and a half has been as I started my first immunotherapy treatment (atezolizumab + FOLFIRI + bevacizumab), as I reported in my earlier...

So this is what GOING OFF-ROADING – EXPERIMENTAL TREATMENT STRATEGY STYLE feels like… What an interesting couple of weeks I have had since my last medical update (link above)!  “Interesting” is a...

Yes, it is time for another medical update! It is funny… the original intent of this blog (before I published the first post) was for it to be a vehicle to...

All I could think to myself was “WOW”!  Similar to my Charlie Rose Show experience last March, this email came out of the blue as well… I received an email from...

First of all, sorry that this post has been delayed so much!  Last year I was able to write up my ASCO post with almost no delay but unfortunately this year my...

I wanted to give an update – both in how things have been going and also what my next plans are (hint: I have to arrive at the hospital for a...

The title says it all, although it should also be noted that this approval also covers other/all MSI-high cancers, not just MSI-HIGH CRC!.  Links below.  The first time a checkpoint immunotherpy (pembrolizumab (Keytruda))...

ASCO-2017 abstracts were released yesterday and there is one study that really stood out for MSS-CRC: Abstract 3002.  The study is for the ongoing clinical trial #NCT02650713 which is testing an exploratory...

>1,000 Hits… my mind was blown away.  My cancer had returned and I was now diagnosed recurrent Stage IV.  I knew at that moment that standard of care therapies would only...

“Ironic” – as shown in the above pictured definition of “Ironic” from the Urban Dictionary – is a word that is often misused in contemporary life but when it comes to...

Cover photo by Ariana Drehsler for STAT.  Source: STAT News – here. As you know I work with MANY different CRC organizations – The WunderGlo Foundation, Fight Colorectal Cancer, COLONTOWN, The...

Both psychologically and practically it is interesting how a cancer patient’s attitude and approach to chemotherapy changes over the course of a “Cancer Career”.  That is a phrase that just popped...

Well… a blog post I certainly don’t want to write and I did not plan on writing… I was told to never bury the lead of a story – so here...

Just a short IMMUNOTHERAPY CLINICAL TRIAL update post today- The phone call just came in last night: The Clinical Trial Countdown Clock has officially started! As a reminder, here is the...

An incredibly intense series of events have been happening to me medically over the past month – life changing events for both me and my family.  Things were happening so quickly,...

This is a blog post I had been hoping to write for a long time! The first published (today in the New England Journal of Medicine) “clinically disease free” success achieved...

SCHEDULED FOR FRIDAY (12/23) – NBC NATIONAL NIGHTLY NEWS with Lester Holt!  NBC Nightly News recently interviewed both I and a patient/caregiver couple helped by the COLONTOWN CLINIC, a project supported by...

In the immortal words of our most recent Nobel Prize Laureate Bob Dylan , the times they are a changin’…  This morning I will be having my final Full Fury (FOLFIRI)...

Cobimetinib  + Atezolizumab  might have grabbed all the Microsatellite Stable-Colorectal Cancer (MSS-CRC) immunotherapy headlines in 2016 but quietly in the background was a second published/presented  Phase 1 Immunotherapy Clinical Trial with...

Pain. I’ve been very fortunate over the past over 4 ½ years since my cancer diagnosis.  I had some pain immediately before my diagnosis from my primary tumor but ever since...

As long time readers of my blog know – I have been in a quandary since I was diagnosed with (presumably cured) Stage 1 melanoma in January 2015.  That diagnosis, even...

Photo graphic courtesy of STAT News, Photo by James Cuevas I hear questions all the time for an update on my personalized “neoantigen” immunotherapy research project – a project I first wrote about...

Hope – it is such a simple, yet complex word. A short word that is easy to explain on the base-level but it can be incredibly complex to comprehend all the...

I had my post-summer-chemo-break CT-scan on Wednesday.  Regrets & worry started to try to enter my consciousness.  They were unwelcome invaders and to be honest, rarely seen or felt in my...

The CT-guided lung biopsy mentioned in my previous post was completed today at the University of Michigan without complications! It is intended to provide both DNA and RNA sequencing data for my personalized...

What do you do when two fully qualified major medical centers give you opposite medical advice?  What do you do when the decision impacts your personal colorectal cancer (CRC) immunotherapy research...

This post is primarily for Stage IV colorectal (CRC) survivor and caregiver readers (and indirectly for Stage IV lung cancer readers as well, see below!): An interview with a Dr. Johanna...

I just wanted to give a brief personal medical update and my related summer plans! With the exception of my diagnosis summer (2012) when potentially curative chemo was given ASAP, I...

To complete the trilogy of posts on the major new preliminary MSS Colorectal Cancer (CRC) immunotherapy results released today on the combination therapy of the MEK inhibitor cobimetinib + the PDL1...

I usually only do this kind of “real-time trial news” post on my Facebook or Twitter accounts but this is such BIG news, I wanted to publish here as well to...

As I promised in my last post “Czech Please!” it is now ASCO season, so be prepared for a science post…  This one is a little hardcore – but bear with...

A very brief medical update! Being hit by a FOLFIRI chemo infusion today only 48 hours after running the team triathlon truly feels bizarre… But that is one of the crazy...

Surfing the AACR Waves of Science What a day.  I just woke up from a drug-induced nap that wasn’t particularly long but it was deep.  For the second FOLFIRI chemo infusion...

It’s hard to believe that it has already been almost 12 months since I last ran a UCSD-Moores Cancer Center Team Triathlon, which I wrote about last year in my post...

You know those moments in life when something so unexpected, so exhilarating & so meaningful (all wrapped up in one) happens – that each time you think of it you get...

To begin with, my CT scan was good – my tumors are shrinking from the FOLFIRI + Avastin chemotherapy I am currently taking!  I have had a 4 week break –...

“Each patient’s cancer is unique and personalized – why shouldn’t their treatment be too?” My latest The Currently Incurable Scientist column for Fight Colorectal Cancer has published and it ended with the...

To start off year #2 of my blog and to kick off the New Year, instead of looking back (I did that with my recent post “World in My Eyes (Favorite...

As I announced in my most recent medical update post “It’s a Marathon Not a Sprint”, this week I started the chemotherapy cocktail FOLFIRI  + the angiogenesis inhibitor Avastin (bevacizumab). I...

My most recent The Currently Incurable Scientist column published this week on the Fight Colorectal Cancer  website.  It explains in layman’s terms the mechanism of action & the very unique and promising...

I don’t normally write blog posts so close together but I know everyone has been curious what my new treatment plan would be after I announced 3 weeks ago that I...

I wanted to expand the normal scope of my personal blog in today’s post. Not just for the sake of expansion but importantly because I believe strongly in today’s topic!  After...

The September edition of my monthly The Currently Incurable Scientist column has published on the Fight Colorectal Cancer website.  It briefly discusses in layman’s terms the profound roles chronic inflammation is...

Some posts are closer to my heart than others.  This one is very close – it shows what made me the patient-scientist-advocate I am today… and it comes down to Mom....

For readers interested in “the science” of current & potential future CRC treatments – my latest monthly column of The Currently Incurable Scientist has been published on the Fight Colorectal Cancer website. ...

The first “science” column of my new patient advocacy writing project “The Currently Incurable Scientist” on the Fight Colorectal Cancer website has been published! As I discussed in the last post – I am...

There is no new medical news to report – which in the case of someone with Stage IV cancer is a good thing!  I’m continuing my weekly Erbitux infusions (with appropriate...

A DVR reminder of a film I have mentioned before: The incredible new Ken Burns “Cancer – the Emperor of All Maladies” PBS mini-series will air next week on Mon-Wed (4/30-5/1),...